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Cataracts are thought to be the cause of 51% of blindness cases, as reported by the World Health Organization (WHO) [5]

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118-123 Specifically, Fitzgerald et al

186 Interestingly, insulin-induced ROS might induce necrosis by initiating PI3K/AKT, a prosurvival pathway, 187 suggesting context-specific ROS modulation of necroptosis (Fig