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Kyle UG, Bosaeus I, De Lorenzo AD, Deurenberg P, Elia M, Gmez JM, Heitmann BL, Kent-Smith L, Melchior J-C, Pirlich M, Scharfetter H, Schols AMWJ, Pichard C: Bioelectrical impedance analysis--part I: review of principles and methods

(2023) identified anti-inflammatory peptides such as SIWYGPDRP (Figure 32), which inhibits nitric oxide (NO) production by 52%, offering potential therapies for chronic inflammation and autoimmune disorders [196]

Conclusive evidence shows that ApoE4 contributes to the development of AD, likely through both a loss-of-function in neuroprotection and a gain-of-function in neurotoxicity, when compared to ApoE3 (Huang and Mucke, 2012