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the disequilibrium of immune-neuro-endocrine networks in psychiatric disorders

Burgetova A, Dusek P, Uher T, Vaneckova M, Vejrazka M, Burgetova R, et al

Therefore, it is reasonable using supplementation of liposomal glutathione, instead of the N-acetylcysteine or bonded cysteine utilized as precursors for GSH cell synthesis, since patients with deficient levels of glutamate-cysteine ligase and GSH synthetase will not be able to use N-acetylcysteine or bonded cysteine as substrates to synthesize their own GSH

Ubiquitination-proteasome system (UPS) and autophagy two main protein degradation machineries in response to cell stress