Ondansetron is a selective serotonin 5-HT3 receptor antagonist used to prevent nausea and vomiting caused by chemotherapy, radiation therapy, and surgery

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In addition to liver-derived serum IGF-1 (endocrine), there is strong evidence that locally expressed IGF-1 (autocrine/paracrine) regulates longitudinal bone growth in the growth plate [87,127132]
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