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(PubMed) Chen Y, Fang B, Hu X, et al

Both were cleverly concealed, even after eight centuries

For example, the Y390-containing loop is positioned in a manner similar to our original SCF FBXO22 structure with UNC10088 C and NSD2 versus the BACH1-bound structure, suggesting that the two regions function independently to recruit substrates with minimal interference

Moreover, we selected 5 mg/kg LicoA for the subsequent verification after the preliminary experiments, this dosage selection aligns with findings reported in a previous study ( Renal tubular epithelial cell (RTEC) injury and death are central to the pathogenesis and progression of CKD (Zhao et al., 2023)