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[5] Disruption of these pathways leads to accumulation of homocysteine and methylmalonic acid, metabolic signatures linked to megaloblastic anemia and demyelinating neuropathy

Methods Search Process We followed the search process set out in our previous meta-analysis ACC GSH studies ( * OR psychos * OR psychot * ) AND (1H-MRS OR 1H NMRS OR 1HMRS OR MRS OR Magnetic resonance spectroscopy OR Spectroscopy OR proton magnetic resonance spectroscopy) AND (glutathione OR GSH)

Wright, David M

In turn, the peroxynitrites inactivate the precursor of nitric oxide synthase (NOS) by increasing the uncoupling of the enzyme creating a greater quantity of O2 - (peroxide) than of NO (47-49)