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Quantification of SUMOylation assays was performed through densitometry analysis using ImageLab (BioRad) to quantify the volume of the ~ 95 kDa anti-HA bands from the immunoprecipitation standardized to the anti-GFP pulldown

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1 Introduction Hericium erinaceus , classified within the kingdom Fungi, phylum Ascomycetes, and family Boletaceae, is a notable edible and medicinal mushroom commonly referred to as the monkey head mushroom