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Indeed, IGF-1 treatment of cultured myotubes blocked myostatin-mediated downregulation of Akt and myotube diameter reduction [23]

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This aligns with how CMS recoups advance investment payments from ACOs whose advance investment payments are involuntarily terminated due to failure to comply with advance investment payment eligibility requirements at 425.316(e)(3) and with the repayment requirements at 425.630(g)(4), if an ACO chooses to terminate from the Shared Savings Program