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Smaller LDL particles have been associated with a more significant state of oxidative stress, according to studies, which may be present in asymptomatic people (Kovaevi et al., 2022) In addition, smaller LDL particles were linked to circulating inflammatory biomarkers before any clinical proof of atherosclerosis (Viktorinova et al., 2021)

The Hospital VBP Program will use data that are also used to calculate quality measures in other programs and Medicare FFS claims data that hospitals are already submitting to CMS for payment purposes, so therefore the program does not anticipate any change in burden associated with these proposed measures

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