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Ruvkun earned this recognition for his contributions to the discovery of microRNA, a new class of tiny RNA molecules that plays a crucial role in gene regulation (see more on page 5)

In mice, bile acids can breach the BBB by activating the nuclear receptor farnesoid X receptor (FXR) in the ileum

PD is characterized by an altered gut microbiota composition, the intestinal barrier, and the enteric neuroimmune system, therefore it is possible that intestinal barrier dysfunction may play a key role in PD development and/or progression

Persistence in antigen expression could differentiate vaccines employing adenovirus vectors from the rest, and this feature is thought to favor the generation of long-term immune responses and prolonged immunity (82, 85)