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doi: 10.3390/biom9080356

Laragione, T

A.AkinleyeM

Endogenous IL-1 has been reported to be insufficient for activating and recruiting neutrophils, and even high pharmacological doses of IL-1 fail to exacerbate APAP-induced liver injury, indicating that IL-1 signaling is not a critical contributor to APAP-induced hepatotoxicity