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Cell culture studies have shown that phenobarbital (PB), phenytoin (PHT), primidone (PRM), carbamazepine (CBZ), oxcarbazepine and felbamate induce CYP3A4 expression, whereas ethosuximide (ETHS), valproic acid (VPA), and lamotrigine (LTG) have no effect on CYP3A4 activity 60, 61

Biological role of TST in mitochondrial processes Mitochondria, often referred to as the powerhouse of the cell, exhibit remarkable plasticity and dynamism, enabling cells to adapt and respond to various environmental stressors and metabolic demands [1]

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Serum citrullinated histone H3 concentrations differentiate patients with septic verses non-septic shock and correlate with disease severity