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Nonspecific binding-fundamental concepts and consequences for biosensing applications

Since the homeostasis of iron in cells depends on the dynamic balance between its absorption, output and utilization, and thusly, the transport, metabolism and storage of iron should be strictly regulated

The hepatic cytochrome P450 system, crucial for herbal constituent metabolism, demonstrates altered functionality in advanced CKD, potentially compromising the biotransformation of complex phytochemical matrices and increasing susceptibility to hepatotoxic reactions (Chen et al., 2021)

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