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Once produced or ingested, vitamin D undergoes hydroxylation in the liver to form 25-hydroxyvitamin D [25(OH)D], the main circulating form used to assess vitamin D status, and then in the kidneys to produce the active hormone 1,25-dihydroxyvitamin D

The Treat and Reduce Obesity Act, which would allow Medicare to cover FDA-approved anti-obesity medications, has been reintroduced in multiple congressional sessions

The consequences of impaired methylation pathways are devastating and result in reduced activity of proteins, reduced production of brain neurotransmitters (seretonin, dopamine, GABA etc), increased inflammation, decreased production of glutathione, alterations in DNA and in cell membrane signaling