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J Hazard Mater Adv 16:100490 Kumar S, Dubey RS, Tripathi RD, Chakrabarty D, Trivedi PK (2015) Omics and biotechnology of arsenic stress and detoxification in plants: current updates and prospective

In contrast, in situ self-assembly systems represent an advanced delivery strategy, with their core innovation being engineered molecular components (e.g., peptides, polymers) that remain in injectable sol states under physiological conditions but spontaneously undergo molecular recognition and binding within the pathological microenvironment of IVDD, characterized by low pH, elevated ROS levels, and enzyme overexpression

doi: 10.1186/s12933-020-01166-6 4 ScurtFGGanzMJHerzogCBoseKMertensPRChatzikyrkouC

26 Genome Wide Association Studies (GWAS) identified 178 genetic risk loci and proposed over 200 candidate gene, using of biobank data, novel imputation methods, combined with clinical cases improved the ability to identify MDD specific pathways