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Men may suffer testicular atrophy (shrinking), infertility, and gynecomastia (male breast growth), while women can develop masculine features not to mention mood swings (roid rage), acne, and hair loss

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NO is a potent vasodilator, and low levels of intracellular ROS play a crucial role in normal redox signaling that helps to maintain vascular function and integrity under physiological conditions (122)