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Originally developed in the 1980s through groundbreaking research identifying the active fragment of naturally occurring GHRH, this 29-amino acid peptide has been investigated in over 50 published studies examining its ability to stimulate endogenous growth hormone secretion

The historically important question, which has been the subject of frequent discussions, is whether oxidative stress is the primary cause or secondary consequence of the disease

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They also highlight the need for longitudinal trials using standardized IF protocols to assess endocrine and metabolic outcomes