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Description

For immune-focused analysis, we manually selected pathways from Gene Ontology (GO) Biological Processes, KEGG, BioCarta, WikiPathways, Reactome, and Hallmarks MsigDB collections, grouping them into three categories: cytokine, antigen processing/presentation and other immune-related

A total of 8554 genes presenting a significantly positive ( n = 4572) or negative ( n = 3982) correlation with aging were selected for further analysis