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Psychopharmacology 237 , 27392752 (2020)

In ferroptosis, accumulation of intracellular iron ions triggers an elevated production of free radicals, potentially surpassing the cellular reductive capacity

Acetylated lysine 56 on histone H3 drives chromatin assembly after repair and signals for the completion of repair

The exact mechanisms of PACS may be multiply overlapping, several hypotheses have been proposed, including persistent viral existence in tissues, dysfunction of vascular endothelium and nervous system, reactivation of latent pathogens and gut microbiota alteration, long-lasting inflammation, and immune dysregulation (Davis et al., 2023)