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Hyperammonemia in children: on the crossroad of different disorders

Research shows: 50% degrades within 30 minutes more than 90% by 2 hours When it complexes with copper, everything changes: it becomes enzyme-resistant far more stable capable of transdermal penetration The copper remains biologically silent until it reaches target cells, making the complex both effective and safe

Optimizing CAR-T cell therapy requires multiple antigen-targeting strategies, such as dual- and trivalent CAR constructs directed against EGFRvIII, IL13R2, and EphA2, reducing the likelihood of immune escape