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We used an AGC target of 2.0e5, and a maximum injection time of 50 ms

Indeed, blocking the recruitment of these cells into the CNS provides significant neuroprotection in preclinical PD models [28]

While the primary endpoints were not met, the preservation of C-peptide levels, as observed in previous studies, suggests that teplizumab may have a role in delaying the progression of T1D [46]