hypothesis glutathione persister cells The macrophage–bacterium mismatch in formation: Trends in Microbiology Exploiting phenotypic heterogeneity to improve

Abundant clinical research has demonstrated that these mechanisms are involved in NAFLD/NASH

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doi: 10.1111/j.1463-1318.2006.01030.x

58 By using error-prone PCR, the combined mutant S131Y/Q252I was obtained, resulting improved activity (214 U mg 1 versus 120 U mg 1 for wild-type enzyme) and the half-deactivating temperature (T50, for 15 min incubation, increased by 2.3 C)