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J Med Plants Stud 5(5):99110 Bhardwaj P (2010) Oxidative stress and antioxidants in gastrointestinal diseases

E2 decline also promotes mitochondrial fission, resulting in fragmented mitochondria with disorganized cristae and reduced inter-organelle connectivity

Further studies should assess the appropriate dose of curcumin to achieve the greatest benefits and determine whether curcumin can enhance the effect of standard-of-care treatment in limiting OSMF disease progression