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Figure 1 3.3 The regulation of macrophage polarization 3.3.1 Metabolic reprogramming and macrophage polarization Metabolic reprogramming is defined as the alterations in bioenergetic pathways in activated immune cells, including glucose metabolism, amino acid metabolism, and fatty acid metabolism ( Glucose metabolism is related to inflammatory responses mediated by macrophage activation

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Consider increased clinical or laboratory monitoring for medications that have a narrow therapeutic index or that require clinical monitoring Use in Specific Populations Pregnancy: Available data with semaglutide use in pregnant women are not sufficient to determine a drug associated risk for major birth defects, miscarriage, or other adverse maternal or fetal outcomes