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Senescent macrophages release inflammatory cytokines and RNA-loaded extracellular vesicles to circumvent fibroblast senescence

Date: June 28, 2013 Event: ociety of Community Research and Action Biennial Meeting Location: Miami, FL Justin Michael Williams Factors leading to treatment entry and initial reactions to 12-Step Recovery among young adults

Specifically, free ferric iron is shuttled into cells bound by transferrin (TF), and reduced to ferrous iron via catalyzing by endosomal six-transmembrane epithelial antigen of prostate 3 (STEAP3), subsequently ferrous iron is released into the cytoplasm through divalent metal transporter 1 (DMT1) to expand the labile iron pool (LIP) (Xu et al., 2024)