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The loss of Nf1 transiently promotes self-renewal but not tumorigenesis by neural crest stem cells

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However, providing L-glutamine alone does not always guarantee a significant increase in glutathione levels, as the body also requires cysteine and glycine

P53-induced activation of antioxidant genes enhances the cellular antioxidant capacity, which is substantiated by increased synthesis of reduced glutathione (GSH), production of NADPH, and detoxification of electrophiles and oxidants