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So Selye began to suggest that subjecting an animal to prolonged stress led to tissue changes and physiological changes with the release of certain hormones, that would then cause disease and ultimately the death of the animal." And so the idea of stress and it's potential costs to the body was born

As the story goes, in the years that followed adolescent smoking rates in Needham declined dramatically and much more than in the towns surrounding Needham that maintained a tobacco purchasing age of 18

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