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Rodriguez-Segade S, Alonso de la Pea C, Paz M, Novoa D, Romero R, Arcocha V et al (1986) Carnitine concentrations in dialysed and undialysed patients with chronic renal insufficiency

2.4 Inflammatory microenvironment Since Rudolf Virchow proposed the close relationship between inflammation and tumor in 1863, more and more studies have confirmed that chronic inflammation is an important marker of tumor occurrence and progression (3)

Since the liver is a major metabolic organ, liver disease is associated with metabolic diseases, such as obesity, insulin resistance, type 2 diabetes (T2DM), and cardiovascular disease

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