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Most tobacco products, including e cigarettes, contain nicotine, a chemical that can harm the heart, brain and whole body. As with other addictive products, using a nicotine product builds tolerance, leading to more Nicotine: The Good, The Bad & The Ugly Echelon Health Nicotine is highly addictive and affects both the brain and body. Whether it's vaping or smoking, nicotine can lead to dependence, cravings, and serious health risks over time. Understanding how nicotine works Nicotine Tobacco, Addiction, Poison Britannica
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