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*Correspondence: Ruchira Salunkhe, [email protected] This article was submitted to Ethnopharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

This matters clinically because blood vessel growth is a rate-limiting step in healing

The predictivity of compounds, that are substrates of the two transporters, could not be improved by this rule

Humans have sought substances to improve our cognitive function for centuries, from ancient civilizations using hallucinogens in an attempt to raise their consciousness to commune with their gods, to the rise of coffee, to the more recent development of drugs such as stimulants and glutamate activators