Major Ingredients [Foaming Gel] Water, Ammonium Lauryl Sulfate, Glycerin, 1,2-Hexanediol, Lauryl Glucoside, Cocamidopropyl Betaine, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Hydrolyzed Sodium Hyaluronate(9,740 ppm), Tromethamine, Sodium Chloride, Citric Acid, Sodium Benzoate, Glutathione(300 ppm), Disodium EDTA, Hydrogenated Lecithin, Maltodextrin, Polyglyceryl-10 Stearate, Polyglyceryl-4 Caprate, Hydrolyzed Gardenia Florida Extract, Butylene Glycol, Niacinamide, Glyceryl Glucoside, Silybum Marianum Extract, Dimethylsilanol Hyaluronate(300 ppb), Sodium Hyaluronate(200 ppb), Polyglyceryl-10 Laurate, Hyaluronic Acid(50 ppb), Hydrolyzed Hyaluronic Acid(50 ppb), Hydroxypropyltrimonium Hyaluronate(50 ppb), Potassium Hyaluronate(35 ppb), Copper Tripeptide-1, Sodium Acetylated Hyaluronate(15 ppb), Acetyl Hexapeptide-8, Cyanocobalamin, Pyridoxine HCl, Palmitoyl Pentapeptide-4, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Riboflavin, Fragrance, Hexyl Cinnamal [Ampoule] Water, Butylene Glycol, 1,2-Hexanediol, Glycerin, Niacinamide, Hydrogenated Coconut Oil, Hydrolyzed Sodium Hyaluronate(9,749 ppm), Cetearyl Alcohol, Glutathione(6,000 ppm), Glyceryl Stearate, Hydrogenated Lecithin, C14-22 Alcohols, Polyglyceryl-10 Stearate, Cetearyl Olivate, Methyl Glucose Sesquistearate, Isoamyl Laurate, Carbomer, Sorbitan Olivate, Polyglyceryl-4 Caprate, Tromethamine, Sodium Hyaluronate(1,000 ppm), Thujopsis Dolabrata Branch Extract, Betaine, Abies Sibirica Oil, Cryptomeria Japonica Leaf Extract, Citrus Junos Peel Oil, Phyllostachys Pubescens Shoot Bark Extract, Chamaecyparis Obtusa Leaf Extract, C12-20 Alkyl Glucoside, Hydrolyzed Hyaluronic Acid(700 ppm), Hyaluronic Acid(700 ppm), Xanthan Gum, Pentylene Glycol, Adenosine, Disodium EDTA, Maltodextrin, Hydrolyzed Gardenia Florida Extract, Glyceryl Glucoside, Ethylhexylglycerin, Glucose, Silybum Marianum Extract, Polyglyceryl-10 Laurate, Dimethylsilanol Hyaluronate(300 ppb), Copper Tripeptide-1, Acetyl Hexapeptide-8, Cyanocobalamin, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Palmitoyl Pentapeptide-4, Pyridoxine HCl, Hydroxypropyltrimonium Hyaluronate(50 ppb), Potassium Hyaluronate(35 ppb), Sodium Acetylated Hyaluronate(15 ppb), Riboflavin, Fragrance, Citronellol, Geraniol, Hexyl Cinnamal, Hydroxycitronellal, Limonene, Linalool [Cream] Water, Glycereth-26, Methylpropanediol, Butylene Glycol, Glycerin, 1,2-Hexanediol, Niacinamide, Neopentyl Glycol Diheptanoate, Rice Ferment Filtrate (Sake)Polyglyceryl-3 Methylglucose Distearate, PEG-240/HDI Copolymer Bis-Decyltetradeceth-20 Ether, Caprylic/Capric Triglyceride, Phenyl Trimethicone, Glyceryl Stearate, Cyclopentasiloxane, PEG-60 Hydrogenated Castor Oil, Cyclohexasiloxane, Ammonium Acryloyldimethyltaurate/VP Copolymer, C12-16 Alcohols, Glutathione(990 ppm), Palmitic Acid, Hydrogenated Lecithin, Ethylhexylglycerin, Adenosine, Diospyros Kaki Fruit Extract, Chloramine T, Sodium Bicarbonate, Sodium Carbonate, Propanediol, Sodium Hyaluronate Crosspolymer(50 ppm), Prunella Vulgaris Extract, Fucus Vesiculosus Extract, Hydrolyzed Glycosaminoglycans(30 ppm), Glycine, Sodium Hyaluronate(15 ppm), Serine, Glutamic Acid, Potassium Laurate, Benzyl Glycol, Aspartic Acid, Leucine, BHT, Alanine, Lysine, Arginine, Tyrosine, Phenylalanine, Threonine, Proline, Valine, Isoleucine, Hydrolyzed Hyaluronic Acid(2.5 ppm), Histidine, Methionine, Cysteine, Ectoin, Ceramide NP, Carbonated Water, Panthenol, Glyceryl Glucoside, Xylitylglucoside, Anhydroxylitol, Xylitol, Hyaluronic Acid(0.05 ppm), Hydrolyzed Collagen, Polyglyceryl-10 Laurate, Polyglyceryl-10 Stearate, Raspberry Ketone, Pantolactone, Sodium Ascorbyl Phosphate, Tripeptide-1, Hexapeptide-9, Acetyl Tetrapeptide-5, Copper Tripeptide-1, Biotin, Acetyl Tetrapeptide-2, Palmitoyl Pentapeptide-4, Hexapeptide-11, Pyridoxine, Folic Acid, Acetyl Hexapeptide-8, Palmitoyl Tripeptide-1, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-5, Tocopherol, Cyanocobalamin, Alanine/Histidine/Lysine Polypeptide Copper HCl, Tripeptide-32, Linoleic Acid, Riboflavin, Beta-Carotene, Inositol, Thiamine HCl, Disodium EDTA, Fragrance [Sun Serum] Water, Propanediol, Butyloctyl Salicylate, Dibutyl Adipate, Ethylhexyl Triazone, Terephthalylidene Dicamphor Sulfonic Acid, Niacinamide, Tromethamine, Polyglyceryl-3 Distearate, Octyldodecanol, Cetearyl Alcohol, 1,2-Hexanediol, Pentylene Glycol, Diethylamino Hydroxybenzoyl Hexyl Benzoate, Caprylyl Methicone, Polysilicone-15, Stellaria Media (Chickweed) Extract, Helianthus Annuus (Sunflower) Flower Extract, Vaccinium Vitis-Idaea Fruit Extract, Caesalpinia Spinosa Fruit Extract, Kappaphycus Alvarezii Extract, Cimicifuga Racemosa Root Extract, Opuntia Ficus-Indica Fruit Extract, Silybum Marianum Extract, Oenothera Biennis (Evening Primrose) Oil, Sodium Hyaluronate(1.6 ppb), Hydrogenated Lecithin, Polymethylsilsesquioxane, Butylene Glycol, Glyceryl Stearate, Bis-Ethylhexyloxyphenol Methoxyphenyl Triazine, Potassium Cetyl Phosphate, Methylpropanediol, Poly C10-30 Alkyl Acrylate, Carbomer, Glyceryl Stearate Citrate, Acrylates/C10-30 Alkyl Acrylate Crosspolymer, Ethylhexylglycerin, Ammonium Acryloyldimethyltaurate/VP Copolymer, Adenosine, Polyether-1, Biosaccharide Gum-1, Panthenol, Tocopherol, Glycerin, Glutathione(100 ppb), Ectoin, Glyceryl Polymethacrylate, Glyceryl Glucoside, Maltodextrin, Hydrolyzed Vegetable Protein, Propylene Glycol, Sodium Hyaluronate Crosspolymer(5.08 ppb), Dimethylsilanol Hyaluronate(0.15 ppb), Resveratrol, Retinyl Palmitate, Biotin, Benzyl Glycol, Cyanocobalamin, Ceramide NP, Sodium Acetylated Hyaluronate(0.04 ppb), Sodium Ascorbyl Phosphate, Sodium Hyaluronate Dimethylsilanol(0.05 ppb), Acetyl Hexapeptide-8, Copper Tripeptide-1, Caprylyl Glycol, Tocopheryl Acetate, Tripeptide-1, Thiamine HCl, Palmitoyl Tetrapeptide-7, Palmitoyl Tripeptide-1, Palmitoyl Pentapeptide-4, Potassium Hyaluronate(0.1 ppb), Polyglyceryl-10 Stearate, Folic Acid, Pyridoxine, Phytosphingosine, Hydroxypropyltrimonium Hyaluronate(0.08 ppb), Hydrolyzed Glycosaminoglycans, Hydrolyzed Sodium Hyaluronate(0.15 ppb), Hydrolyzed Hyaluronic Acid(0.4 ppb), Hyaluronic Acid(0.105 ppb), Hexapeptide-9, Fragrance Ingredients subject to change at manufacturer's discretion
Consistent with this, endogenous BDNF colocalizes with secretory granule markers such as furin in neurons, is preferentially sorted to the RSP, and is released in an activity-dependent manner [23,24,25]
These beneficial effects were dose-dependent and were abrogated when the ER signaling pathway was inhibited, but off-target systemic side effects have not been investigated
Kojic acid is optimally active around pH 45
