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If we considered the situation of S-crystallin in the lens, it is important for this protein to capture GSH for as long as possible and to minimize its catalytic activity, otherwise the GSH will be released as a product conjugate

a low mass tolerance of 5 ppm mass error

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Ultimately, combination therapies grounded in multi-target and personalized strategies are poised to play a transformative role in the clinical management of DCM, offering hope for more effective and patient-specific treatments in the future