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d , Plasmin concentrations in cell culture supernatant from 4T1 mammary tumour cells overexpressing empty vector, PLGRKT, PLGRKT K147R , and PLGRKT 139-147 (n = 9 individual wells)

10.1016/j.freeradbiomed.2010.09.006 129 RiddickD

Heme oxygenase-1 (HO-1), a cytoprotective enzyme, was upregulated upon treatment with erastin or RSL3 in renal proximal tubule cells, while deletion of HO-1 increased the cellular susceptibility to erastin-induced ferroptosis [37]