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PLoS One 8 , e81162 (2013)

There may be mild soreness in the muscle for a few hours afterward, but it's rarely severe enough to interfere with daily activities

doi: 10.1016/j.ebiom.2022.104258 43 DollSFreitasFPShahRAldrovandiMda SilvaMCIngoldIet al

The MAGE-A3/titin experience showed that even modest affinity enhancement can cause severe organ toxicity, underscoring the narrow therapeutic window of some targets [192, 193]