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7 Therapeutic strategies and clinical translation With the deepening understanding of ferroptosis mechanisms, an increasing number of molecular targets have been identified as closely associated with the pathological progression of AD

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In individuals especially for those dealing with metabolic disorders like type 2 diabetes, obesity, and nonalcoholic fatty liver disease (NAFLD), curcumin supplementation has been shown to significantly reduce markers of oxidative stress and inflammation, including Malondialdehyde (MDA) can be referred to as a lipid peroxidation product, while tumor necrosis factor-alpha (TNF-) is often described as a pro-inflammatory cytokine

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