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High-intensity interval training (HIIT) two to three times per week provides metabolic benefits that steady-state cardio cannot match

In DKD, stimuli such as ROS, hyperglycemia, Ang II, hypoxia, and inflammation indirectly activate TGF-1 by inducing TSP-1 production (170172)

Vitamin D may also exert a protective effect on the kidneys: studies in animal models suggest the active form of vitamin D may suppress kidney inflammation, fibrosis, and cell death