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This has been attributed to increased mechanical fragility (iron deficient RBC are more rigid and more likely to fragment as they traverse through small capillaries under high shear), however oxidative injury to red blood cells is likely contributing to keratocyte formation (Yoo et al 2009) (given that antioxidant enzymes in red blood cells, such as glutathione peroxidase, contain iron)

In addition, the combination of zonulin levels, gender, and abdominal symptoms, can differentiate NCGS from IBS with a diagnostic accuracy of 89% (141)

Because of the systemic nature of BPC 157 signaling, it is mandatory that users work under the close supervision of a licensed healthcare practitioner or a specialist in regenerative medicine

doi: 10.1007/s12035-015-9355-3 81 KalinskiP