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Disorders in several upstream signalling pathways of translation, including mTOR, Ras and MAPK pathways, contribute to increased protein synthesis and therefore to altered synaptic plasticity (Fig

It is a two ATP-requiring enzymatically catalyzed process.[] After its synthesis, glutathione gets distributed in intracellular organelles, including endoplasmic reticulum (ER), nucleus, and mitochondria.[] NUCLEAR GLUTATHIONE In the nucleus, GSH prevents the oxidation of sulfhydryl groups of several proteins to disulfide groups

Beniwal N, Verma A, Putta CL, Rengan AK