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Everolimus in neuroendocrine tumors of the gastrointestinal tract and unknown primary

Microvasc Res 75(2):144154 Funahashi Y et al (2010) Notch regulates the angiogenic response via induction of VEGFR-1

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They are therefore less toxic (LD 50 = 1000-2000 mg/kg) than the cyanogenic compounds above, though they may cause toxicity by other means, e.g