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B12: Plays an essential role in red blood cell formation, DNA synthesis, cell metabolism, nerve function, and hormone balance

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239 In an uncontrolled trial that included 15 women with fibromyalgia, seven of whom had also been diagnosed with chronic fatigue syndrome, treatment with a synbiotic (probiotic/prebiotic combination) for 30 days decreased stress, anxiety, and depression, improved quality of life, and reduced IL-8 levels