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Description

Nat Rev Microbiol 17:247260

These results confirm that ubiquitylation of IL-1 at K133 is required for efficient proteasomal degradation of TLR-induced IL-1

Researchers who evaluate their protocol at week 8 are seeing titration-phase results, not maintenance-phase results

Authors contributions Research design (XL, KZ, FW, JC), literature search and evidence synthesis (XL, RD, PJ, XtW, GG, XW, CX, HL), and writing of the manuscript (XL, RD)