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BDNF/NGF Pathway Enhancers (Lions Mane, 7,8-DHF) Mechanism: These aim to upregulate neurotrophins or mimic TrkB signaling, nudging plasticity

To evaluate the functional significance of these spine changes Nlel-AnglV and Dihexa stimulated hippocampal neurons were immunostained against the glutamatergic presynaptic marker VGLUT1 (Balschun, Moechars et al