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However, given the putative importance of neuroinflammation in this condition, we believe that the ME/CFS neuroimaging field could benefit from basing a priori targeting of brain regions of interest in the newly emerging human neuroinflammation literature recently meta-analyzed by Kraynak et al

The same procedures were applied to the control group but this time saline was used

Therefore, we postulated in this study that oxidative stress stimulated in DCM induced the activation of NLRP3 and the ensuing pyroptosis, thereby governing the death of cardiomyocytes and activation of fibroblasts

Drug solutions, typically 5 mg/ml in HPLC-grade water (except for Dihexa, prepared in DMSO), were added to rat serum, and the mixture was incubated at 37C