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[29] [39] Kekul used evidence that had accumulated in the intervening yearsnamely, that there always appeared to be only one isomer of any monoderivative of benzene, and that there always appeared to be exactly three isomers of every disubstituted derivativenow understood to correspond to the ortho, meta, and para patterns of arene substitutionto argue in support of his proposed structure

Regulatory scientists and industry partners must be engaged early to ensure scale-up and global dissemination

In a recent study by Serra et al, 151 a lumbar fixator with the anatomical shape of an IVD was developed using 3D printing technology, enabling the fabrication of artificial IVDs