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[PMC free article: PMC4500284] [PubMed: 26100900] ABSTRACT INTRODUCTION TARGETS OF PHARMACOTHERAPY IN THE MANAGEMENT OF OBESITY CENTRALLY-ACTING ANTI-OBESITY DRUGS GASTROINTESTINAL AND PANCREATIC PEPTIDES THAT REGULATE FOOD INTAKE PERIPHERAL MODULATORS OF THE EFFICIENCY OF DIGESTION, METABOLISM, AND LIPOGENESIS ALTERNATIVE AND COMPLEMENTARY TYPES OF TREATMENT OF OBESITY CONCLUSION REFERENCES Review Pharmacologic Treatment of Overweight and Obesity in Adults.[Endotext

One well-known cause is pernicious anemia

There is no benefit to these over traditional supplements and you're at risk of excessive B12 levels and other possible risks such as infection

It is important to note that these side effects are relatively uncommon and, when they do occur, are usually mild and temporary