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Rapid proliferation, high protein synthesis rates, hypoxia, nutrient deprivation, acidosis, and oxidative stress collectively impose a severe folding burden on the ER

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J Immunol 143(6):19741981 Mohr S, Zech B, Lapetina EG, Brune B (1997) Inhibition of caspase-3 by S-nitrosation and oxidation caused by nitric oxide

As more plants become reliant upon relatively aggressive makeup water from nonstandard sources such as high-conductivity well waters and municipal gray waters, the use of galvanized steel for cooling tower construction should start to diminish