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Intake of higher doses doesnt appear to be associated with detrimental health problems.2 The VNDPG recommends the following B12 guidance2: All vegetarians, regardless of type, should periodically be screened for B12 deficiency, using either methylmalonic acid (MMA) or TCII (transcobalamin) assessment

Dietary and supplementary betaine: effects on betaine and homocysteine concentrations in males

This is why many patients benefit from ongoing, personalized therapy rather than a fixed treatment course

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