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Chronic inflammation: Sustained immune activation that erodes tissues

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A 2006 study using rat models concluded that vitamin E administrationas either a high-dose single injection (0.1, 1, or 5 g/kg with no equivalent human dose owing to variations in metabolic rates between species) or repetitive daily low-dose injections (50 or 100 mg/kg, equating to 3 g in a 60-kg human)reduced behaviors associated with mechanical allodynia