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The Arabidopsis AtOPT3 protein functions in metal homeostasis and movement of iron to developing seeds

For example, the activation of inflammasomes, especially the NLRP3 inflammasome, leads to endothelial dysfunction, plaque formation, and myocardial injury by inducing the release of pro-inflammatory cytokines such as IL-1, IL-18, and IL-6 ( 5.1 The anti-inflammatory effect in atherosclerosis Silybin has been shown to reduce the inflammatory response in atherosclerotic lesions, with its core mechanism involving the direct inhibition of key pro-inflammatory signaling pathways

Similarly, the repurposing of anti-inflammatory agents such as aspirin has demonstrated preclinical efficacy in preserving DA neurons [298]

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