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Mitochondria link metabolism and epigenetics in haematopoiesis

Hun conclusie was dat beide behandeltrajecten even effectief waren

doi: 10.1016/0162-3109(89)90020-9 113 HarveyC

Therefore, a decrease in xCT inhibits the intracellular import of cysteine, leading to less glutathione synthesis, lower GPX4 activity, and ultimately the accumulation of lipid hydroperoxides, which is linked to loss of plasma membrane integrity 35